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Injections Of Corticosteroids Or Platelet-Rich Plasma: Which Is Better For Joint Pain?

We are sorry if this causes any difficulty but keeping up with the rapidly growing medical field may be difficult for anybody. Still, one constant is the fact that people will always face a wide range of health problems, injuries, and other challenges. The majority of doctors today still utilize cortisone and its derivatives injections to treat a wide variety of conditions and injuries.

Cortisone injections may be helpful in the short term, but it’s crucial to remember that repeated or prolonged usage can damage tissues and lead to unpleasant side effects. PRP, or platelet-rich plasma, is a key component. Platelet-rich plasma (PRP) injections may be used instead of corticosteroid injections; however they don’t have the same negative side effects. In this article, we will take a brief look at some intriguing medical study that pits the two against one other to see which one is more effective. Who will come out on top in this conflict? First, however, let’s establish some terminology for best alternatives to cortisone shots.

Learning About Platelet-Rich Plasma (PRP) Blood Plasma with a High Number of Platelets

Plasma, along with RBCs and WBCs, is a possible component of all blood types. They’re crucial to the body’s ability to clot blood. Plasma also contains growth factors, which are crucial to the practice of regenerative medicine since they aid in the regenerating process and alleviate your symptoms. Large volumes of your plasma are being sent to the area of the body that needs it most to begin the mending process. Concentrating the plasma and reintroducing it to the damaged part of the body is how this is done. The tissue in your body may self-heal thanks to the growth hormones that stimulate the production of new cells. If you tap or click here, you’ll be sent to an article explaining PRP in further detail.

A Deeper Dive into Corticosteroids

This is a helpful drug for alleviating inflammation. This synthetic corticosteroid is similar to the naturally occurring hormone cortisol. Cortisone helps alleviate joint swelling and pain, as well as treat inflammation caused by conditions like autoimmune disease. Its natural counterpart, cortisol, is produced by the adrenal glands in the body. This hormone dampens the immune system’s inflammatory and allergic responses. Synthetic cortisone mimics the action of cortisol and, although it often has the desired effect, it also carries the danger of potentially more serious side effects for the patient.

Clinical Trials Comparing Platelet-Rich Plasma with Corticosteroids

Forty patients with osteoarthritis were treated in a study published in the Journal of Orthopedic Surgery and Research in 2020. Half of the group was treated with cortisone injections, while the other half received platelet-rich plasma (PRP) injections. For the duration of the treatment and for up to a year following the last injection, the results were monitored.


Neither group ultimately showed any adverse reactions. This, though, is when things begin to take an intriguing turn. Pain relief and improvement in the corticosteroids group persisted through week 15 of the research. Patients undergoing CS showed regressive behavior after the 15th week of therapy, and the pain made its way back into their life.

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